Accueil - CRCL - C3D - Centre de découverte et de développement du médicament

Camille Jouines, Piero Lo Monaco, Angéline Gaucherot, Julie Radermecker, Caroline Isaac, et al.. Fibrillarin-mediated ribosomal RNA maturation is a novel therapeutic vulnerability in triple-negative breast cancer. Breast Cancer Research, 2025, ⟨10.1186/s13058-025-02163-x⟩. ⟨hal-05005111⟩
François Virard, Stéphane Giraud, Mélanie Bonnet, Léa Magadoux, Laetitia Martin, et al.. Targeting ERK-MYD88 interaction leads to ERK dysregulation and immunogenic cancer cell death. Nature Communications, 2024, 15, pp.7037. ⟨10.1038/s41467-024-51275-z⟩. ⟨hal-04676566⟩
Alaa Al Assi, Solène Posty, Frédéric Lamarche, Amel Chebel, Jérôme Guitton, et al.. A novel inhibitor of the mitochondrial respiratory complex I with uncoupling properties exerts potent antitumor activity. Cell Death and Disease, 2024, 15 (5), pp.311. ⟨10.1038/s41419-024-06668-9⟩. ⟨hal-04566195⟩
Hermes Paraqindes, Nour-El-Houda Mourksi, Samantha Ballesta, Jordan Hedjam, Fleur Bourdelais, et al.. Isocitrate dehydrogenase wt and IDHmut adult-type diffuse gliomas display distinct alterations in ribosome biogenesis and 2’O-methylation of ribosomal RNA. Neuro-Oncology, 2023, ⟨10.1093/neuonc/noad140⟩. ⟨hal-04203242⟩
Camille Libre, Ludovic Moro-Sibilot, Stéphane Giraud, Laetitia Martin, Els Verhoeyen, et al.. Development of a Model for Chemical Screening Based on Collateral Sensitivity to Target BTK C481S Mutant. Cancers, 2020, 12 (4), pp.901. ⟨10.3390/cancers12040901⟩. ⟨hal-04654379⟩

Derniers manuscrits de la plateforme

Chiffres clés